The effects of a very large dose of opium
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The effects of a very large dose of opium

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Published by G. Hamilton and J. Balfour in Edinburgh .
Written in English


  • Opium.,
  • Narcotics -- Physiological effect.

Book details:

Edition Notes

Statementby David Clerk.
SeriesLandmarks of science II
LC ClassificationsQ111 .H35, SB295.O6 .H35
The Physical Object
Paginationp. 121-128.
Number of Pages128
ID Numbers
Open LibraryOL19448460M

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Opium (Papaver somniferum) is a CNS depressant and narcotic analgesic; it is not a hallucinogen. It exerts its effects through specific opiate receptors (ORs) (such as mu (MOR), delta (DOR), kappa (KOR), nociceptin receptor (NOP)). Opium smoking was a very ancient, traditional, and . Reddish-brown and extremely bitter, laudanum contains almost all of the opium alkaloids, including morphine and um was historically used to treat a variety of conditions, but its principal use was as a pain medication and cough the early 20th century, laudanum was sold without a prescription and was a constituent of many patent medicines. Eating large amounts might cause caffeine-related side effects such as nervousness, increased urination, sleeplessness, and a fast heartbeat. Cocoa can cause allergic skin reactions, constipation. Opium is a naturally occurring analgesic harvested as a latex from ripe Papaver somniferum (opium poppy) pods. It has a long history of use by humans as an oral and smoked psychoactive. BOOKS # The Big Smoke: The Chinese Art & Craft of Opium, by Peter Lee. Confessions of an English Opium .

If dextromethorphan is taken in very high doses, it has effects similar to methamphetamine Morphine and codeine are derived from the opium poppy, Papaver somniferum Opium smoking was widespread in .   -Dose of 1 mg/kg/day appears to be equally efficacious and may result in fewer behavioral side effects Maximum dose: 60 mg/day Duration of therapy: 3 to 10 days Age: 12 years or older: Short-course "burst" therapy: 40 to 80 mg orally once a day or in 2 divided doses .   A study on rats indicated that subcutaneous administration of buprenorphine in doses of , and mg/kg reduces QT time and increases heart rate. This dose-dependent effect is reversible at low and medium doses (, mg/kg) but not at high doses (15 mg/kg). In the United States, buprenorphine is mostly supplied in combination.   It has since been updated to reflect current statistics and data, and to provide additional information on the side effects and long-term effects of opioid use. Lee Weber is the main writer, editor, and voice behind Addiction Blog, an online journal that documents alcohol, drug and prescription drug addiction and its treatment.

Puerperal convulsions may demand doses as high as 10 gr. Opium in moderate doses (1/2 to 1 gr.; tr., 5 to I0 I. ; Dover's Powder, 5 to 8 gr.) is indicated in many cases of diarrhea and for a diaphoretic effect. The moderate dose, especially of Dover's Powder, is indicated. While these drugs are often very effective in treating pain, people can eventually develop a tolerance, so they require higher doses to achieve the same effects. As the effects of opiate drugs become more tolerated, people may begin taking increasingly higher doses to experience the same pain-relieving effects and to reduce symptoms of withdrawal.   “Uterine and ovarian complications cause more ladies to fall into the [opium] habit, than all other diseases combined,” wrote Dr. Frederick Heman Hubbard in his book, The Opium . Among patients with acute pain, chronic opium abusers are a real challenge (), as they usually need extremely high doses of analgesics for acute pain suppression, and in addition, some analgesics are not very effective on them (6, 7). To resolve this problem, many analgesics have been tested with controversial results.